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pentobarbital will lower the level or influence of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers could decrease partiaprevir and ritonavir levels, and for that reason diminished efficacy of Viekira PakContraindicated (one)pentobarbital decrease